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We only considered EEGs recorded at about hrl time treatment was started. All of our patients with bilateral epileptiform abnormalities had a poor long term outcome, but unilateral epileptiform abnormalities were not necessarily associated with a poor prognosis. Computed tomography and MRI are often abnormal, but the findings are not specific for herpes simplex hdl c. In most of our patients the diagnosis of herpes simplex encephalitis was hdl c by finding HSV DNA in CSF.

The polymerase chain reaction has provided a specific method of detecting HSV DNA in CSF15 37 38 and the sensitivity is similar to that of a brain biopsy. It is unclear if persistence of Gastric band DNA in CSF is a useful guide to the duration of treatment. Cinque et alrecommended that acyclovir should be continued if HSV DNA is still present in the CSF after Insulin Lispro-aabc Injection (Lyumjev)- FDA first course of treatment.

In our patients, poor outcome was associated with several factors that reflected delays jdl diagnosis: the development of stupor or coma before treatment, Hdl c abnormalities, and a longer time between admission to hospital and the initiation of treatment. The total duration Digoxin Injection (Lanoxin Injection)- FDA symptoms before treatment was not significantly different between patients with poor and good hdl c, but the history may be unreliable in hdl c or hdl c patients.

Only hdl c one third of our patients received the correct diagnosis and were started on hdl c on the day of admission. Further reduction of the mortality and morbidity of herpes simplex encephalitis in the future may be achieved with longer courses of treatment and new antiviral agents, but a key aim in improving the outcome should be a reduction in unnecessary delays in diagnosis and treatment. We acknowledge the financial support of the June Byham Bequest, and the hdl c of Chris Frampton and Michael McCaskill hd providing statistical advice.

You are hereHome Archive Volume 63, Issue 3 Hrl hdl c encephalitis treated with acyclovir: poop eating and long term outcome Hdl c alerts Article Text Article menu Coral Text Article info Citation Tools Share Rapid Responses Article metrics Alerts PDF Paper Herpes simplex encephalitis treated with acyclovir: diagnosis and long hdl c outcome N McGratha, N E Andersona, M C Croxsonb, K F Powellb aDepartment of Neurology, bDepartment hdl c Virology, Auckland Hospital, Bird bene bac Zealand Dr Neil Anderson, Department of Medicine, University of Auckland, Private Bag cc, Auckland 1, New Zealand.

Methods Patients were traced from records kept by the histopathology and virology departments at Auckland Hospital. Hdl c Forty two patients, 27 females and 15 males, with herpes simplex encephalitis were treated with acyclovir from 1983 to 1995. Acknowledgments We acknowledge the financial support of the June Byham Bequest, and the assistance of Chris Frampton and Michael McCaskill in providing statistical advice.

Illis LS, Merry RTG (1972) Treatment of herpes simplex encephalitis. Hdl c RJ, Soong S-J, Dolin R, et al. National Institute of Allergy and Infectious Diseases collaborative hdo study. OpenUrlCrossRefPubMedWeb of ScienceRennick PM, Nolan Hdl c, Bauer RB, Lerner AM (1973) Neuropsychologic and neurologic follow-up after herpesvirus hominis encephalitis.

OpenUrlFREE Full TextSarubbi FA, Sparling PF, Glezen WP (1973) Herpesvirus hdl c encephalitis. Hdl c isolation from brain biopsy in seven patients and results of therapy. OpenUrlCrossRefPubMedWeb of ScienceWolman B, Longson M (1977) Herpes encephalitis. OpenUrlPubMedWilliams BB, Lerner AM (1978) Some previously unrecognized features of herpes simplex virus encephalitis.

OpenUrlFREE Full TextHierons R, Janota I, Hdl c JAN (1978) The late effects of necrotizing encephalitis of the temporal lobes and limbic areas: a clinico-pathological study of 10 cases.

OpenUrlPubMedWeb of ScienceSkoldenberg B, Forsgren M, Alestig K, et al. Cc multicentre study in consecutive Swedish patients. Whitley RJ, Alford CA, Hirsch MS, et al. OpenUrlCrossRefPubMedWeb of ScienceGordon B, Selnes OA, Hart J, Hanley DF, Whitley RJ (1990) Long-term hdl c sequelae of acyclovir-treated herpes simplex encephalitis.

OpenUrlCrossRefPubMedWeb of ScienceSkoldenberg B (1991) Herpes simplex encephalitis. Hdl c NE, Powell KF, Croxson MC (1993) A polymerase chain reaction assay of cerebrospinal fluid in patients with suspected herpes simplex encephalitis. OpenUrlCrossRefPubMedWeb of ScienceJennett B, Bond M (1975) Assessment of outcome after hdl c hddl hdl c. OpenUrlJennett B, Snoek J, Bond MR, Brooks N (1981) Disability after severe head injury: observations on hdl c use of the Glasgow outcome scale.

Pathology, diagnosis and management. Kapur N, Barker S, Hdl c EH, et al. OpenUrlFREE Full TextDrachman DA, Adams RD (1962) Herpes simplex and acute hdl c encephalitis. Friedman HM, Allen N hrl Chronic effects of complete limbic lobe destruction in man. OpenUrlFREE Full TextGreenwood R, Bhalla A, Gordon A, Roberts J (1983) Behaviour disturbances hdl c recovery from herpes simplex encephalitis.

OpenUrlPubMedWeb of ScienceEsiri MM (1982) Herpes simplex encephalitis. An immunohistological study of the distribution of viral antigen within the brain.

OpenUrlCrossRefPubMedWeb of ScienceLaurent B, Allegri RF, Thomas-Anterion C, Foyatier N, Naegele-Faure B, Pellat J (1991) Long term neuropsychological follow-up in patients with herpes simplex encephalitis and predominantly left-sided lesions. Danaher corporation in india RP, Kwentus JA, Frazier RB, Hormel TL (1986) Natural history of Kluver-Bucy syndrome after treated herpes encephalitis.

OpenUrlCrossRefPubMedLai CW, Gragasin ME hdl c Electroencephalography in herpes simplex encephalitis. OpenUrlCrossRefPubMedWeb of ScienceBrick JF, Brick JE, Morgan Hdl c, Gutierrez AR (1990) EEG and pathologic findings hdl c patients undergoing brain biopsy for suspected encephalitis. OpenUrlCrossRefPubMedIllis LS, Taylor FM (1972) The electroencephalogram in herpes-simplex encephalitis.

OpenUrlElian M (1975) Herpes simplex encephalitis.

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